Publikationen

• ausgewählte
• 2010
• 2009
• 2008
• 2007
• 2006
• 2005
• 2004
• 2003
• 2002
• 2001
• 2000

Ausgewählte Publikationen
(letzter 5-Jahres-Impact-Faktor größer 7; in chronologischer Reihenfolge)

Structure and biochemical analysis of the heparin-induced E1 dimer of the amyloid precursor protein

Dahms SO, Hoefgen S, Roeser D, Schlott B, Gührs KH, Than ME

Proc Natl Acad Sci 2010 (epub ahead of print)

Wt1 and Retinoic Acid Signaling in the Subcoelomic Mesenchyme Control the Development of the Pleuropericardial Membranes and the Sinus Horns

Norden J, Grieskamp T, Lausch E, van Wijk B, van den Hoff MJB, Englert C, Petry M, Mommersteeg MTM, Christoffels VM, Niederreither K, Kispert A

Circulation Research 2010 (epub ahead of print)

Mouse aorta smooth muscle cells differentiate into lymphoid tissue organizer-like cells upon combined TNFR1/LTβR NF-κB signaling

Lötzer K, Döpping S, Connert S, Gräbner R, Spanbroek R, Lemser B, Beer M, Hildner M, Hehlgans T, van der Wall M, Mebius RE, Lovas A, Randolph GJ, Weih F*, Habenicht AJR *

Arterioscler Thromb Vasc Biol 2009, 30, 395-402 *equal contribution

Increased skeletal VEGF enhances β-catenin activity and results in excessively ossified bones

Maes C, Goossens S, Bartunkova S, Drogat B, Coenegrachts L, Stockmans I, Moermans K , Nyabi O, Haigh K , Naessens M, Haenebalcke L, Tuckermann JP, Tjwa M, Carmeliet P, Mandic V, David J-P, Behrens A, Nagy A, Carmeliet G, Haigh JJ

EMBO Journal 2010, 29, 424-41

Mechanism of amyloid plaque formation suggests an intracellular basis of Abeta pathogenicity.

Friedrich RP, Tepper K, Rönicke R, Soom M, Westermann M, Reymann K, Kaether C, Fändrich M

Proc.Natl.Acad.Sci.USA 2010, epub ahead of print January 19

Nucleolar retention of a translational C/EBPα isoform stimulates rDNA transcription and cell size

Müller C, Bremer A, Schreiber S, Eichwald S, Calkhoven CF

EMBO Journal 2010, epub ahead of print January 19

EBMO Journal_pdf

C/EBPβ^ΔuORFmice—a genetic model for uORF-mediated translational control in mammals

Wethmar K, Begay V, Smink JJ, Zaragoza K, Wiesenthal V, Dörken B, Calkhoven CF, Leutz A

Genes & Development 2010, 24, 15-20

Alpha2-macroglobulin inhibits the malignant properties of astrocytoma cells by impeding beta-catenin signaling

Lindner I, Hemdan NY, Buchold M, Huse K, Bigl M, Oerlecke I, Ricken A, Gaunitz F, Sack U, Naumann A, Hollborn M, Thal D, Gebhardt R, Birkenmeier G

Cancer Research 2010, 70, 277-87

Mutations in FAM134B, encoding a newly identified Golgi protein, cause severe sensory and autonomic neuropathy

Kurth I, Pamminger T, Hennings JC, Soehendra D, Huebner AK, Rotthier A, Baets J, Senderek J, Topaloglu H, Farrell SA, Nürnberg G, Nürnberg P, De Jonghe P, Gal A, Kaether C, Timmerman V, Hübner CA

Nature Genetics 2009 (epub ahead of print)

X-chromosomal variation is associated with slow progression to AIDS in HIV-infected women

Siddiqui RA, Sauermann U, Altmüller J, Fritzer E, Nothnagel M, Dalibor N, Fellay J, Kaup FJ, Stahl-Hennig C, Nürnberg P, Krawczak M, Platzer M

American Journal of Human Genetics 2009, 85, 228-239

A highly conserved retinoic acid responsive element controls wt1a expression in the zebrafish pronephros

Bollig F, Perner B, Besenbeck B, Köthe S, Ebert C, Taudien S, Englert C

Development 2009, 136, 2883-2892

In vivo PEPCK promoter mapping identifies disrupted hormonal synergism as a target of inflammation during sepsis in mice

Chichelnitskiy E, Vegiopoulos A, Berriel Diaz M, Ziegler A, Kleiman A, Rauch A, Tuckermann J, Herzig S

Hepatology 2009 (epub ahead of print)

Polyketide assembly lines of uncultivated sponge symbionts from structure-based gene targeting

Fisch KM, Gurgui C, Heycke N, van der Sar SA, Anderson SA, Webb VL, Taudien S, Platzer M, Rubio BK, Robinson SJ, Crews P, Piel J

Nature Chemical Biology 2009, 5, 494-501

Scribble participates in Hippo signaling and is required for normal zebrafish pronephros development

Skouloudaki K, Puetz M, Simons M, Courbard JR, Boehlke C, Hartleben B, Engel C, Moeller MJ, Englert C, Bollig F, Schäfer T, Ramachandran H, Mlodzik M, Huber TB, Kuehn EW, Kim E, Kramer-Zucker A, Walz G

Proc Natl Acad Sci USA 2009, 106, 8579-84

The PGD2 pathway, independently of FGF9, amplifies SOX9 activity in Sertoli cells during male sexual differentiation

Moniot B, Declosmenil F, Barrionuevo F, Scherer G, Aritake K, Malki S, Marzi L, Cohen-Solal A, Georg I, Klattig J, Englert C, Kim Y, Capel B, Eguchi N, Urade Y, Boizet-Bonhoure B, Poulat F

Development 2009, 136, 1813-1821

Systematic Evaluation of the Effect of Common SNPs on Pre-mRNA Splicing

ElSharawy A, Hundrieser B, Brosch M, Wittig M, Huse K, Platzer M , Rosenstiel P, Schreiber S , Krawczak M , Hampe J

Human Mutation 2009, 30, 625-632

Effects of dietary restriction on mortality and age-related phenotypes in the short-lived fish Nothobranchius furzeri

Terzibasi E, Lefrançois C, Domenici P, Hartmann N, Graf M, Cellerino A

Aging Cell 2009, 8, 88-99

DNA methylation analysis of chromosome 21 gene promoters at single base pair and single allele resolution

Zhang Y, Rohde C, Tierling S, Jurkowski TP, Bock C, Santacruz D, Ragozin S, Reinhardt R, Groth M, Walter J, Jeltsch A

PLoS Genet. 2009 Mar;5(3):e1000438

High tandem repeat content in the genome of the short-lived annual fish Nothobranchius furzeri: a new vertebrate model for aging research.

Reichwald K, Lauber C, Nanda I, Kirschner J, Hartmann N, Schories S, Gausmann U, Taudien S, Schilhabel MB, Szafranski K, Glöckner G, Schmid M, Cellerino A, Schartl M, Englert C, Platzer M

Genome Biology 2009 Feb 11;10(2):R16

Lymphotoxin β receptor signaling promotes tertiary lymphoid organogenesis in the aorta adventitia of aged ApoE^–/– mice

Gräbner R, Lötzer K, Döpping S, Hildner M, Radke D, Beer M, Spanbroek R, Lippert B, Reardon CA, Getz GS, Fu Y-X, Hehlgans T, Mebius RE, van der Wall M, Kruspe D, Englert C, Lovas A, Hu D, Randolph GJ, Weih F, Habenicht AJR

J Exp Med 2009, 206, 233-48

A phosphorylation-acetylation switch regulates STAT1 signaling

Kramer OH, Knauer SK, Greiner G, Jandt E, Reichardt S, Guhrs KH, Stauber RH, Bohmer FD, Heinzel T

Genes & Development 2009, 23, 223-235

Critical role of macrophages in glucocorticoid driven vascular calcification in a mouse-model of atherosclerosis

Preusch MR, Rattazzi M, Albrecht C, Merle U, Tuckermann J, Schütz G, Blessing E, Zoppellaro G, Pauletto P, Krempien R, Rosenfeld ME, Katus HA, Bea F

Arterioscler Thromb Vasc Biol. 2008, 28, 2158-64

The wave property of heavy molecules - Its use in mass spectrometry

Greulich KO

Angew Chem Int Ed Engl. 2008, 47, 7990-7991.

Lack of NF-kappaB2/p100 causes a RelB-dependent block in early B lymphopoiesis

Guo F, Tänzer S, Busslinger M, Weih F

Blood. 2008, 112, 551-559.

Paired {beta}-sheet structure of an A{beta}(1-40) amyloid fibril revealed by electron microscopy

Sachse C, Fändrich M, Grigorieff N

Proc Natl Acad Sci USA. 2008, 105, 7462-7466.

SNP and haplotype mapping for genetic analysis in the rat

STAR Consortium, Saar K, Beck A, Bihoreau MT, Birney E, Brocklebank D, Chen Y, Cuppen E, Demonchy S, Dopazo J, Flicek P, Foglio M, Fujiyama A, Gut IG, Gauguier D, Guigo R, Guryev V, Heinig M, Hummel O, Jahn N, Klages S, Kren V, Kube M, Kuhl H, Kuramoto T, Kuroki Y, Lechner D, Lee YA, Lopez-Bigas N, Lathrop GM, Mashimo T, Medina I, Mott R, Patone G, Perrier-Cornet JA, Platzer M, Pravenec M, Reinhardt R, Sakaki Y, Schilhabel M, Schulz H, Serikawa T, Shikhagaie M, Tatsumoto S, Taudien S, Toyoda A, Voigt B, Zelenika D, Zimdahl H, Hubner N

Nat Genet. 2008, 40, 560-566.

Widespread and subtle: alternative splicing at short-distance tandem sites

Hiller M, Platzer M

Trends Genet. 2008, 24, 246-255.

Opposing effects of dietary protein and sugar regulate a transcriptional target of Drosophila insulin-like peptide signaling

Buch S, Melcher C, Bauer M, Katzenberger J, Pankratz MJ

Cell Metab. 2008, 7, 321-332.

Chromatophore genome sequence of paulinella sheds light on acquisition of photosynthesis by eukaryotes

Nowack EC, Melkonian M, Glöckner G

Curr Biol. 2008, 18, 410-418.

Dynamics of inner kinetochore assembly and maintenance in living cells

Hemmerich P, Weidtkamp-Peters S, Hoischen C, Schmiedeberg L, Erliandri I, Diekmann S

J Cell Biol. 2008, 180, 1101-1114.

Centromere anatomy in the multidrug-resistant pathogen Enterococcus faecium

Derome A, Hoischen C, Bussiek M, Grady R, Adamczyk M, Keedzierska B, Diekmann S, Barillà D, Hayes F

Proc Natl Acad Sci USA. 2008, 105, 2151-2156.

Supreme enLIGHTenment: damage recognition and signaling in the mammalian UV response

Herrlich P, Karin M, Weiss C

Mol Cell. 2008, 29, 279-290.

Exploiting the mosaic structure of trans-acyltransferase polyketide synthases for natural product discovery and pathway dissection

Nguyen T, Ishida K, Jenke-Kodama H, Dittmann E, Gurgui C, Hochmuth T, Taudien S, Platzer M, Hertweck C, Piel J

Nat Biotechnol. 2008, 26, 225-233.

Reciprocity between phase shifts and amplitude changes in the mammalian circadian clock

Pulivarthy SR, Tanaka N, Welsh DK, De Haro L, Verma IM, Panda S

Proc Natl Acad Sci USA. 2007, 104, 20356-20361.

Directed selection of a conformational antibody domain that prevents mature amyloid fibril formation by stabilizing Abeta protofibrils

Habicht G, Haupt C, Friedrich RP, Hortschansky P, Sachse C, Meinhardt J, Wieligmann K, Gellermann GP, Brodhun M, Götz J, Halbhuber K-J, Röcken C, Horn U, Fändrich M

Proc Natl Acad Sci USA. 2007, 104, 19232-19237.

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Endogenous transforming growth factor beta1 suppresses inflammation and promotes survival in adult CNS

Makwana M, Jones LL, Cuthill D, Heuer H, Bohatschek M, Hristova M, Friedrichsen S, Ormsby I, Bueringer D, Koppius A, Bauer K, Doetschman T, Raivich G

J Neurosci. 2007, 27, 11201-11213.

The TATA-binding protein regulates maternal mRNA degradation and differential zygotic transcription in zebrafish

Ferg M, Sanges R, Gehrig J, Kiss J, Bauer M, Lovas A, Szabo M, Yang L, Straehle U Pankratz MJ, Olasz F, Stupka E, Muller F

EMBO Journal 2007, 26, 3945-3956

Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns

Szafranski K, Schindler S, Taudien S, Hiller M, Huse K, Jahn N, Schreiber S, Backofen R, Platzer M

Genome Biol. 2007, 8, R154.

Constitutive alternative NF-kappaB signaling promotes marginal zone B-cell development but disrupts the marginal sinus and induces HEV-like structures in the spleen

Guo F, Weih D, Meier E, Weih F

Blood. 2007, 110, 2381-2389.

Endoplasmic reticulum retention of the gamma-secretase complex component Pen2 by Rer1

Kaether C, Scheuermann J, Fassler M, Zilow S, Shirotani K, Valkova C, Novak B, Kacmar S, Steiner H, Haass C

EMBO Rep. 2007, 8, 743-748.

(pdf)

Macrophages and neutrophils are the targets for immune suppression by glucocorticoids in contact allergy

Tuckermann JP, Kleiman A, Moriggl R, Spanbroek R, Neumann A, Illing A, Clausen BE, Stride B, Förster I, Habenicht AJ, Reichardt HM, Tronche F, Schmid W, Schütz G

J Clin Invest. 2007, 117, 1381-1390.

Comment in Cell 129, May 18, 2007 (Immunology Select)

Endosymbiont-dependent host reproduction maintains bacterial-fungal mutualism

Partida-Martinez LP, Monajembashi S, Greulich KO, Hertweck C

Curr Biol. 2007, 17, 773-777.

Skin inflammation in RelB-/- mice leads to defective immunity and impaired clearance of vaccinia virus

Freyschmidt EJ, Mathias CB, MacArthur DH, Laouar A, Narasimhaswamy M, Weih F, Oettgen HC

J Allergy Clin Immunol. 2007, 119, 671-679.

Abnormal thyroid hormone metabolism in mice lacking the monocarboxylate transporter 8

Trajkovic M, Visser TJ, Mittag J, Horn S, Lukas J, Darras VM, Raivich G, Bauer K, Heuer H

J Clin Invest. 2007, 117, 627-635.

see also: Editorial in Nature Clinical Practice (July 2007)

Merlin/neurofibromatosis type 2 suppresses growth by inhibiting the activation of ras and rac

Morrison H, Sperka T, Manent J, Giovannini M, Ponta H, Herrlich P

Cancer Res. 2007, 67, 520-527.

A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1

Hampe J, Franke A, Rosenstiel P, Till A, Teuber M, Huse K, Albrecht M, Mayr G, De La Vega FM, Briggs J, Günther S, Prescott NJ, Onnie CM, Häsler R, Sipos B, Fölsch UR, Lengauer T, Platzer M, Mathew CG

Nat Genet. 2007, 39, 2007-2011.

Conditional deletion of Nbs1 in murine cells reveals its role in branching repair pathways of DNA double-strand breaks

Yang YG, Saidi A, Frappart PO, Min W, Barrucand C, Dumon-Jones V, Michelon J, Herceg Z, Wang ZQ

EMBO J. 2006, 25, 5527-5538.

SNPSplicer: systematic analysis of SNP-dependent splicing in genotyped cDNAs

ElSharawy A, Manaster C, Teuber M, Rosenstiel P, Kwiatkowski R, Huse K, Platzer M, Becker A, Nürnberg P, Schreiber S, Hampe J

Hum Mutat. 2006, 27, 1129-1134.

Sequencing errors or SNPs at splice-acceptor guanines in dbSNP?

Platzer M, Hiller M, Szafranski K, Jahn N, Hampe J, Schreiber S, Backofen R, Huse K

Nat Biotechnol. 2006, 24, 1068-1070.

Constraints on the structure of (CUG)97-RNA from MAS solid state NMR spectroscopy

Riedel K, Herbst C, Häfner S, Leppert J, Ohlenschläger O, Swanson MS, Görlach M, Ramachandran R

Angew Chem Int Ed Engl. 2006, 45, 5620-5623.

Tumorigenic transformation by CPI-17 through inhibition of a merlin phosphatase

Jin H, Sperka T, Herrlich P, Morrison H

Nature. 2006, 442, 576-579.

Antiinflammatory effects of dexamethasone are partly dependent on induction of dual specificity phosphatase 1

Abraham SM, Lawrence T, Kleiman A, Warden P, Medghalchi M, Tuckermann J, Saklatvala J, Clark AR

J Exp Med. 2006, 203, 1883-1889.

Phylogenetically widespread alternative splicing at unusual GYNGYN donors

Hiller M, Huse K, Szafranski K, Rosenstiel P, Schreiber S, Backofen R, Platzer M

Genome Biol. 2006, 7, R65.

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German human methylome project started

Jeltsch A, Walter J, Reinhardt R, Platzer M

Cancer Res. 2006, 66, 7378.

Should the draft chimpanzee sequence be finished?

Taudien S, Ebersberger I, Glöckner G, Platzer M

Trends Genet. 2006, 22, 122-125

A short isoform of NOD2/CARD15, NOD2-S, is an endogenous inhibitor of NOD2/receptor-interacting protein kinase 2-induced signaling pathways

Rosenstiel P, Huse K, Till A, Hampe J, Hellmig S, Sina C, Billmann S, von Kampen O, Waetzig GH, Platzer M, Seegert D, Schreiber S

Proc Natl Acad Sci USA. 2006, 103, 3280-3285

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A translational control reporter system (TCRS) for the analysis of translationally controlled processes in the vertebrate cell

Wiesenthal V, Leutz A, Calkhoven CF

Nucleic Acids Res. 2006, 34, e23.

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DNA sequence and analysis of human chromosome 8

Nusbaum C, ..., Taudien S, ..., Blechschmidt K, ..., Glöckner G, et al.

Nature. 2006, 439, 331-335.

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