News

June 27, 2014
Steffen Mayerl mit Promotionspreis 2014 der FSU Jena ausgezeichnet » more

June 24, 2014
Tag der Architektur am 28. und 29. Juni » more

June 19, 2014
Best Oral Presentation Award for Harald Schuhwerk » more

  » Overview News


Press Releases

July 9, 2014
Schüler-Sommerschule zum Thema Laser (IPHT) » more

June 27, 2014
Schillertag: Ein Feiertag mit vielen Preisen (FSU) » more

June 24, 2014
Leibniz-Gemeinschaft stärkt interdisziplinäre Alternsforschung » more

  » Overview Press Releases


 

Our Mission

Human ageing is a multifactorial process controlled by both environmental and genetic factors. Our mission is to understand the molecular mechanisms that underlie the ageing process and that lead to age-related diseases. We hope that eventually this knowledge can contribute to a more healthy ageing of people. The central question we are aiming at answering is

 

«What are the molecular mechanisms and genetic factors contributing to the evolution of cellular and organismal dysfunction during human aging?».

 


LFVDoes a healthy way of living in the later phase of our live influences our cognitive performance? How does a balanced nutrition affect the health costs of seniors? Is the ageing process influenced more by genetic or by external factors? These are just a few questions the interdisciplinary Leibniz Research Alliance Healthy Ageing (LRA Healthy Ageing) will focus on during the next years. 20 institutes from all sections of the Leibniz Association have signed the collaboration contract. Prof. Dr. K. Lenhard Rudolph, scientific director of FLI, and Prof. Jean Krutmann (IUF) act as speakers of the Research Alliance. A dedicated website www.leibniz-healthy-ageing.de provides information about all activities and research projects of the LRA Healthy Ageing.
>> Press release 24.06.2014


 

Recent Selected Publications


Physiological state co-regulates thousands of mammalian mRNA splicing events at tandem splice sites and alternative exons
Szafranski K, Fritsch C, Schumann F, Siebel L, Sinha R, Hampe J, Hiller M, Englert C, Huse K, Platzer M
Nucleic Acids Res 2014 (epub ahead of print) [PubMed]

 

RepARK--de novo creation of repeat libraries from whole-genome NGS reads
Koch P, Platzer M, Downie BR
Nucleic Acids Res. 2014, 42, e80 [PubMed]

 

Trrap-dependent histone acetylation specifically regulates cell-cycle gene transcription to control neural progenitor fate decisions
Tapias A, Zhou ZW, Shi Y, Chong Z, Wang P, Groth M, Platzer M, Huttner W, Herceg Z, Yang YG, Wang ZQ
Cell Stem Cell. 2014, 14, 632-643 [PubMed]

 

Wnt7a stimulates myogenic stem cell motility and engraftment resulting in improved muscle strength
Bentzinger CF*, von Maltzahn J*, Dumont NA, Stark DA, Wang YX, Nhan K, Frenette J, Cornelison DD, Rudnicki MA
J Cell Biol. 2014, 205, 97-111 [PubMed]

 

A 'telomere-associated secretory phenotype' cooperates with BCR-ABL to drive malignant proliferation of leukemic cells
Braig M, Pällmann N, Preukschas M, Steinemann D, Hofmann W, Gompf A, Streichert T, Braunschweig T, Copland M, Rudolph KL, Bokemeyer C, Koschmieder S, Schuppert A, Balabanov S, Brümmendorf TH
Leukemia. 2014 (epub ahead of print) [PubMed]

 

» Overview Publications